hrp0086p2-p789 | Pituitary and Neuroendocrinology P2 | ESPE2016

A Patient with Multiple Endocrine Neoplasia Type 1 Presented with Precocious Puberty

Akcan Nese , Mousa Umut , Sav Hasan , Bundak Ruveyde

Background: Multiple Endocrine Neoplasia Type 1 (MEN1) is an autosomally transmitted hyperplastic or neoplastic disorders of some endocrine and non-endocrine organs. Pituiatry tumors develop in 30–70% of patients with MEN1. Mean age at onset of MEN1 associated pituitary tumors is the 4th decade and its occurence before and during puberty is very rare. Although there are two case reports about MEN1 and delay puberty, early and rapidly progressive puberty with MEN1 has no r...